diff --git a/package/libiio/libiio.mk b/package/libiio/libiio.mk
index f706298c22..38b2f83e6e 100644
--- a/package/libiio/libiio.mk
+++ b/package/libiio/libiio.mk
@@ -76,8 +76,10 @@ endif
 ifeq ($(BR2_PACKAGE_LIBIIO_BINDINGS_PYTHON),y)
 ifeq ($(BR2_PACKAGE_PYTHON),y)
 LIBIIO_DEPENDENCIES += host-python-setuptools python
+LIBIIO_CONF_OPTS += -DPYTHON_EXECUTABLE=$(HOST_DIR)/bin/python
 else ifeq ($(BR2_PACKAGE_PYTHON3),y)
 LIBIIO_DEPENDENCIES += host-python3-setuptools python3
+LIBIIO_CONF_OPTS += -DPYTHON_EXECUTABLE=$(HOST_DIR)/bin/python3
 endif
 LIBIIO_CONF_OPTS += -DPYTHON_BINDINGS=ON
 else