diff --git a/Config.in.legacy b/Config.in.legacy
index 3cd78ccf1c..8db9558ed4 100644
--- a/Config.in.legacy
+++ b/Config.in.legacy
@@ -146,6 +146,12 @@ endif
 
 comment "Legacy options removed in 2022.02"
 
+config BR2_PACKAGE_PYTHON_SUBPROCESS32
+	bool "python-subprocess32 removed"
+	select BR2_LEGACY
+	help
+	  Package was removed together with python 2.7 support.
+
 config BR2_PACKAGE_PYTHON_SINGLEDISPATCH
 	bool "python-singledispatch removed"
 	select BR2_LEGACY
diff --git a/package/Config.in b/package/Config.in
index 0261463f45..18de2a32a5 100644
--- a/package/Config.in
+++ b/package/Config.in
@@ -1243,7 +1243,6 @@ menu "External python modules"
 	source "package/python-sqlalchemy/Config.in"
 	source "package/python-sqliteschema/Config.in"
 	source "package/python-sqlparse/Config.in"
-	source "package/python-subprocess32/Config.in"
 	source "package/python-systemd/Config.in"
 	source "package/python-tabledata/Config.in"
 	source "package/python-tempora/Config.in"
diff --git a/package/python-subprocess32/Config.in b/package/python-subprocess32/Config.in
deleted file mode 100644
index d7fe84f1e6..0000000000
--- a/package/python-subprocess32/Config.in
+++ /dev/null
@@ -1,13 +0,0 @@
-config BR2_PACKAGE_PYTHON_SUBPROCESS32
-	bool "python-subprocess32"
-	depends on BR2_PACKAGE_PYTHON
-	depends on BR2_TOOLCHAIN_HEADERS_AT_LEAST_3_10 || !BR2_MIPS_NABI64
-	help
-	  A backport of the Python 3 subprocess module for use
-	  on Python 2.
-
-	  https://github.com/google/python-subprocess32
-
-comment "python-subprocess32 needs a toolchain w/ headers >= 3.10 on MIPS N64"
-	depends on BR2_MIPS_NABI64
-	depends on !BR2_TOOLCHAIN_HEADERS_AT_LEAST_3_10
diff --git a/package/python-subprocess32/python-subprocess32.hash b/package/python-subprocess32/python-subprocess32.hash
deleted file mode 100644
index 65d18763d1..0000000000
--- a/package/python-subprocess32/python-subprocess32.hash
+++ /dev/null
@@ -1,5 +0,0 @@
-# md5, sha256 from https://pypi.org/pypi/subprocess32/json
-md5	748844d560be5f0c707931cba1cdb48b  subprocess32-3.5.4.tar.gz
-sha256	eb2937c80497978d181efa1b839ec2d9622cf9600a039a79d0e108d1f9aec79d  subprocess32-3.5.4.tar.gz
-# Locally computed sha256 checksums
-sha256	826b43437249d39422642f695154d064da64de92eb1476048a615f50bc1beb4a  LICENSE
diff --git a/package/python-subprocess32/python-subprocess32.mk b/package/python-subprocess32/python-subprocess32.mk
deleted file mode 100644
index fb8a47f974..0000000000
--- a/package/python-subprocess32/python-subprocess32.mk
+++ /dev/null
@@ -1,31 +0,0 @@
-################################################################################
-#
-# python-subprocess32
-#
-################################################################################
-
-PYTHON_SUBPROCESS32_VERSION = 3.5.4
-PYTHON_SUBPROCESS32_SOURCE = subprocess32-$(PYTHON_SUBPROCESS32_VERSION).tar.gz
-PYTHON_SUBPROCESS32_SITE = https://files.pythonhosted.org/packages/32/c8/564be4d12629b912ea431f1a50eb8b3b9d00f1a0b1ceff17f266be190007
-PYTHON_SUBPROCESS32_SETUP_TYPE = setuptools
-PYTHON_SUBPROCESS32_LICENSE = Python-2.0
-PYTHON_SUBPROCESS32_LICENSE_FILES = LICENSE
-
-# The configure step needs to be run outside of the setup.py since it isn't
-# run correctly for cross-compiling
-define PYTHON_SUBPROCESS32_CONFIGURE_CMDS
-	(cd $(@D) && \
-	$(TARGET_CONFIGURE_OPTS) \
-	$(TARGET_CONFIGURE_ARGS) \
-	./configure \
-		--target=$(GNU_TARGET_NAME) \
-		--host=$(GNU_TARGET_NAME) \
-		--build=$(GNU_HOST_NAME) \
-		--prefix=/usr \
-		--exec-prefix=/usr \
-		--sysconfdir=/etc \
-		--program-prefix="" \
-	)
-endef
-
-$(eval $(python-package))