diff --git a/package/qt5/qt5base/qt5base.mk b/package/qt5/qt5base/qt5base.mk
index b79059c2a4..b96c2eb04a 100644
--- a/package/qt5/qt5base/qt5base.mk
+++ b/package/qt5/qt5base/qt5base.mk
@@ -33,6 +33,25 @@ else
 QT5BASE_DEPENDENCIES += pcre2
 endif
 
+ifeq ($(BR2_X86_CPU_HAS_SSE2),)
+QT5BASE_CONFIGURE_OPTS += -no-sse2
+else ifeq ($(BR2_X86_CPU_HAS_SSE3),)
+QT5BASE_CONFIGURE_OPTS += -no-sse3
+else ifeq ($(BR2_X86_CPU_HAS_SSSE3),)
+QT5BASE_CONFIGURE_OPTS += -no-ssse3
+else ifeq ($(BR2_X86_CPU_HAS_SSE4),)
+QT5BASE_CONFIGURE_OPTS += -no-sse4.1
+else ifeq ($(BR2_X86_CPU_HAS_SSE42),)
+QT5BASE_CONFIGURE_OPTS += -no-sse4.2
+else ifeq ($(BR2_X86_CPU_HAS_AVX),)
+QT5BASE_CONFIGURE_OPTS += -no-avx
+else ifeq ($(BR2_X86_CPU_HAS_AVX2),)
+QT5BASE_CONFIGURE_OPTS += -no-avx2
+else
+# no buildroot BR2_X86_CPU_HAS_AVX512 option yet for qt configure
+# option '-no-avx512' (available for latest only)
+endif
+
 QT5BASE_CONFIGURE_OPTS += $(call qstrip,$(BR2_PACKAGE_QT5BASE_CUSTOM_CONF_OPTS))
 
 ifeq ($(BR2_PACKAGE_LIBDRM),y)