diff --git a/package/gnuradio/Config.in b/package/gnuradio/Config.in
index 6d0669779f..80f6a1c535 100644
--- a/package/gnuradio/Config.in
+++ b/package/gnuradio/Config.in
@@ -66,11 +66,15 @@ config BR2_PACKAGE_GNURADIO_PYTHON
 	bool "python support"
 	depends on BR2_PACKAGE_PYTHON
 	depends on BR2_PACKAGE_PYTHON_NUMPY_ARCH_SUPPORTS
+	depends on BR2_TOOLCHAIN_USES_GLIBC || BR2_TOOLCHAIN_USES_MUSL # python-numpy
 	select BR2_PACKAGE_BOOST_PYTHON
 	select BR2_PACKAGE_PYTHON_NUMPY # runtime
 	help
 	  Enable python component
 
+comment "python support needs glibc or musl"
+	depends on !(BR2_TOOLCHAIN_USES_GLIBC || BR2_TOOLCHAIN_USES_MUSL)
+
 config BR2_PACKAGE_GNURADIO_UTILS
 	bool "gr-utils support"
 	depends on BR2_PACKAGE_GNURADIO_PYTHON
diff --git a/package/opencv3/Config.in b/package/opencv3/Config.in
index 61405a7c64..c308cd4d87 100644
--- a/package/opencv3/Config.in
+++ b/package/opencv3/Config.in
@@ -157,11 +157,15 @@ config BR2_PACKAGE_OPENCV3_LIB_PYTHON
 	bool "python"
 	depends on BR2_PACKAGE_PYTHON || BR2_PACKAGE_PYTHON3
 	depends on BR2_PACKAGE_PYTHON_NUMPY_ARCH_SUPPORTS
+	depends on BR2_TOOLCHAIN_USES_GLIBC || BR2_TOOLCHAIN_USES_MUSL # python-numpy
 	select BR2_PACKAGE_PYTHON_NUMPY
 	help
 	  Include opencv_python module into the OpenCV build.  No
 	  python example is installed.
 
+comment "python support needs glibc or musl"
+	depends on !(BR2_TOOLCHAIN_USES_GLIBC || BR2_TOOLCHAIN_USES_MUSL)
+
 config BR2_PACKAGE_OPENCV3_LIB_SHAPE
 	bool "shape"
 	# opencv_core dependency is already enabled