diff --git a/package/python-pyhamcrest/Config.in b/package/python-pyhamcrest/Config.in
index c2a4dc06f7..27224cdbf1 100644
--- a/package/python-pyhamcrest/Config.in
+++ b/package/python-pyhamcrest/Config.in
@@ -1,7 +1,5 @@
 config BR2_PACKAGE_PYTHON_PYHAMCREST
 	bool "python-pyhamcrest"
-	select BR2_PACKAGE_PYTHON_SETUPTOOLS # runtime
-	select BR2_PACKAGE_PYTHON_SIX # runtime
 	help
 	  Hamcrest framework for matcher objects.
 
diff --git a/package/python-pyhamcrest/python-pyhamcrest.hash b/package/python-pyhamcrest/python-pyhamcrest.hash
index 176079e0f5..ba230d3a07 100644
--- a/package/python-pyhamcrest/python-pyhamcrest.hash
+++ b/package/python-pyhamcrest/python-pyhamcrest.hash
@@ -1,5 +1,5 @@
 # md5, sha256 from https://pypi.org/pypi/pyhamcrest/json
-md5  c808291b2fca0991d044927884e6d15e  pyhamcrest-2.0.4.tar.gz
-sha256  b5d9ce6b977696286cf232ce2adf8969b4d0b045975b0936ac9005e84e67e9c1  pyhamcrest-2.0.4.tar.gz
+md5  c731efc9bcb93ef4f73d110f5ca8e844  pyhamcrest-2.1.0.tar.gz
+sha256  c6acbec0923d0cb7e72c22af1926f3e7c97b8e8d69fc7498eabacaf7c975bd9c  pyhamcrest-2.1.0.tar.gz
 # Locally computed sha256 checksums
 sha256  71beae6c8151362cfe398cbd350191a1cc52d3d28499839a7830b25f5b50a7fe  LICENSE.txt
diff --git a/package/python-pyhamcrest/python-pyhamcrest.mk b/package/python-pyhamcrest/python-pyhamcrest.mk
index de5295e964..6631ff1d6a 100644
--- a/package/python-pyhamcrest/python-pyhamcrest.mk
+++ b/package/python-pyhamcrest/python-pyhamcrest.mk
@@ -4,11 +4,14 @@
 #
 ################################################################################
 
-PYTHON_PYHAMCREST_VERSION = 2.0.4
+PYTHON_PYHAMCREST_VERSION = 2.1.0
 PYTHON_PYHAMCREST_SOURCE = pyhamcrest-$(PYTHON_PYHAMCREST_VERSION).tar.gz
-PYTHON_PYHAMCREST_SITE = https://files.pythonhosted.org/packages/b1/9a/588f086b64ace8d2e9843d8551e9068b2570c3c51b06cb49a107303f8700
-PYTHON_PYHAMCREST_SETUP_TYPE = setuptools
+PYTHON_PYHAMCREST_SITE = https://files.pythonhosted.org/packages/16/3f/f286caba4e64391a8dc9200e6de6ce0d07471e3f718248c3276843b7793b
+PYTHON_PYHAMCREST_SETUP_TYPE = pep517
 PYTHON_PYHAMCREST_LICENSE = BSD-3-Clause
 PYTHON_PYHAMCREST_LICENSE_FILES = LICENSE.txt
+PYTHON_PYHAMCREST_DEPENDENCIES = \
+	host-python-hatchling \
+	host-python-hatch-vcs
 
 $(eval $(python-package))