diff --git a/package/openssl/Config.in b/package/openssl/Config.in
index e33320afc5..d84033141f 100644
--- a/package/openssl/Config.in
+++ b/package/openssl/Config.in
@@ -48,6 +48,8 @@ endif
 config BR2_PACKAGE_LIBRESSL
 	bool "libressl"
 	depends on !BR2_PACKAGE_OPENSSL_FORCE_LIBOPENSSL
+	# uClibc on noMMU doesn't provide __register_atfork()
+	depends on !(BR2_TOOLCHAIN_USES_UCLIBC && !BR2_USE_MMU)
 	help
 	  LibreSSL is a version of the TLS/crypto stack forked from
 	  OpenSSL in 2014, with goals of modernizing the codebase,