diff --git a/package/wpewebkit/wpewebkit.hash b/package/wpewebkit/wpewebkit.hash
index d5f628e1ee..aaeea2bcda 100644
--- a/package/wpewebkit/wpewebkit.hash
+++ b/package/wpewebkit/wpewebkit.hash
@@ -1,7 +1,6 @@
-# From https://wpewebkit.org/releases/wpewebkit-2.38.6.tar.xz.sums
-md5  eb44d3132208218f3752170cae3220b8  wpewebkit-2.38.6.tar.xz
-sha1  5c541a10e216d8d9ca48572b3dc0f82bfb2236c5  wpewebkit-2.38.6.tar.xz
-sha256  dcb6591456393c5366ad9abc62a808137d4fea039cbc7ef4c8d64ead506d035b  wpewebkit-2.38.6.tar.xz
+# From https://wpewebkit.org/releases/wpewebkit-2.40.3.tar.xz.sums
+sha1  c840bd76b2c86cb8ca0d68b56598cb0abbafc727  wpewebkit-2.40.3.tar.xz
+sha256  05b6a9cb1d7d03485e0dc41b2a8e6f99a36aea23d32ba3ecb38d0d6860747ada  wpewebkit-2.40.3.tar.xz
 
 # Hashes for license files:
 sha256  0b5d3a7cc325942567373b0ecd757d07c132e0ebd7c97bfc63f7e1a76094edb4  Source/WebCore/LICENSE-APPLE
diff --git a/package/wpewebkit/wpewebkit.mk b/package/wpewebkit/wpewebkit.mk
index 7b8ac67d92..c13a7201e6 100644
--- a/package/wpewebkit/wpewebkit.mk
+++ b/package/wpewebkit/wpewebkit.mk
@@ -4,8 +4,8 @@
 #
 ################################################################################
 
-WPEWEBKIT_VERSION = 2.38.6
-WPEWEBKIT_SITE = http://www.wpewebkit.org/releases
+WPEWEBKIT_VERSION = 2.40.3
+WPEWEBKIT_SITE = https://wpewebkit.org/releases
 WPEWEBKIT_SOURCE = wpewebkit-$(WPEWEBKIT_VERSION).tar.xz
 WPEWEBKIT_INSTALL_STAGING = YES
 WPEWEBKIT_LICENSE = LGPL-2.1+, BSD-2-Clause
@@ -14,7 +14,7 @@ WPEWEBKIT_LICENSE_FILES = \
 	Source/WebCore/LICENSE-LGPL-2.1
 WPEWEBKIT_CPE_ID_VENDOR = wpewebkit
 WPEWEBKIT_CPE_ID_PRODUCT = wpe_webkit
-WPEWEBKIT_DEPENDENCIES = host-gperf host-python3 host-ruby \
+WPEWEBKIT_DEPENDENCIES = host-gperf host-python3 host-ruby host-unifdef \
 	harfbuzz cairo icu jpeg libepoxy libgcrypt libgles libsoup libtasn1 \
 	libpng libxslt openjpeg wayland-protocols webp wpebackend-fdo
 
@@ -26,6 +26,7 @@ WPEWEBKIT_CONF_OPTS = \
 	-DENABLE_INTROSPECTION=OFF \
 	-DENABLE_MINIBROWSER=OFF \
 	-DENABLE_WEB_RTC=OFF \
+	-DUSE_AVIF=OFF \
 	-DUSE_SOUP2=ON
 
 ifeq ($(BR2_PACKAGE_WPEWEBKIT_SANDBOX),y)